The VenaEC™ biochip is ideal for studying cell-cell interaction. In the case of the VenaEC™ biochip, endothelial cells are actually seeded and cultured on one surface of the microcapillary and suspension cells or whole blood, can flow over the endothelial cell monolayer, enabling the user to study cell-cell interaction under conditions mimicking physiological flow.
VenaEC™ biochip
Illustration close-up:
Cell adhesion inside cell-cultured microchannel of VenaEC™ biochip
Example: Adhesion of MDA-GFP (breast cancer cell line) on TNF-alpha treated HUVEC cell line at shear stress of 0.5 dyne/cm2
Oncology-Melanoma: GFP-tagged 1205Lu melanoma cells adhering to non-stimulated HUVECs under shear flow
Inflammation - Asthma / COPD: Eosinophil Adhesion to HMVEC-L at 0.5 dyne/cm²
Oncology - Breast Cancer: GFP-tagged MDA cancer cells adhering to non-stimulated HUVECs under flow
Breast Cancer: MDA cells adhering to TNF-alpha stimulated HUVECs under shear flow in microfluidic biochip
Each biochip is supplied with 4 substrates facilitating 8 experiments. Each substrate is tissue culture treated for growing endothelial cells and when assembled contains two capillaries for cellcell interaction studies under shear flow. Each 10 pack is supplied with 40 substrates contains 80assays. Each 5 pack is supplied with 20 substrates contains 40 assays
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