Dynamic Cell Based Assay Model

Cellix products model inflammation microenvironments in vivo. The ability of cells circulating in the bloodstream to adhere to the endothelium, switch to a motile phenotype and penetrate through the endothelial layer is recognised as a necessary pre-requisite for the effective in vivo trafficking of specific lymphocyte sub-populations. This represents a multi-step process currently described as

  1. Margination
  2. Rolling
  3. Activation
  4. Adhesion
  5. Migration

Cellix Ltd, Unit 381, Institute of Molecular Medicine, Trinity Centre for Health Sciences,
James's Street, Dublin 8, Ireland.

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